Is preoperative anemia a risk factor for upper tract urothelial carcinoma following radical nephroureterectomy?
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- 作者：Hsin-Chih Yeh ; M.D. ; M.S.a ; b ; c ; d ; 1 ; Tsu-Ming Chien ; M.D. ; M.S.c ; 1 ; Wen-Jeng Wu ; M.D. ; Ph.D.a ; b ; c ; d ; e ; Ching-Chia Li ; M.D.a ; b ; c ; d ; Wei-Ming Li ; M.D. ; M.Sb ; c ; d ; f ; Hung-Lung Ke ; M.D. ; M.S.b ; c ; d ; Yii-Her Chou ; M.D. ; Ph.D.b ; c ; Chii-Jye Wang ; M.D. ; Ph.D.b ; c ; Shu-Pin Huang ; M.D. ; Ph.D.b ; c ; Chien-Feng Li ; M.D. ; Ph.D.g ; h ; i ; Peir-In Liang ; M.D.j ; Chun-Nung Huang ; M.D. ; Ph.D.b ; c ; slaochain@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Anemia ; Metastasis ; Prognosis ; Upper tract urothelial carcinoma
- 刊名：Urologic Oncology: Seminars and Original Investigations
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：34
- 期：8
- 页码：337.e1-337.e9
- 全文大小：924 K
文摘
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Preoperative anemia was significantly correlated with worse chronic kidney disease (CKD) stage and higher pathological tumor stage in patients with upper tract urothelial carcinoma (UTUC).
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By Kaplan-Meier analysis, preoperative anemia was not significantly associated with metastasis-free and cancer-specific survival for patients with UTUC. However, preoperative anemia well predicted survival in those without stage 5 CKD.
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Patients׳ renal function is important when evaluating anemia in UTUC before radical surgery, which may assist in preoperative counseling, decision making, and even personalized treatment.