The synovial microenvironment of osteoarthritic joints alters RNA-seq expression profiles of human primary articular chondrocytes
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文摘
<p id="p0005">RNA-seq data compared from primary chondrocytes in joints with and without OAp>
<p id="p0010">Human chondrocytes exhibit OA grade-related differences in gene expression.p>
<p id="p0015">Disease-related genes involved in cell-adhesion, ECM production, and immune responsep>
<p id="p0020">Synovial microenvironments directly alter gene expression in chondrocytes.p>
<p id="p0025">Sampling cartilage from OA joints is not an ideal source of healthy chondrocytes.p>

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