Is Caenorhabditis elegans the Magic Bullet for Anthelminthic Drug Discovery?

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• 作者：Jennifer Keiser¹ ; ² ; ^{Jennifer.keiser@unibas.ch" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Caenorhabditis elegans ; drug discovery ; anthelminthics
• 刊名：Trends in Parasitology
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：31
• 期：10
• 页码：455-456
• 全文大小：271 K

文摘

Recent advances in handling and readout have facilitated high-throughput screens with Caenorhabditis elegans. A new study demonstrates that C. elegans is a useful tool in high-throughput anthelminthic drug discovery. Despite challenges, drug discovery using C. elegans offers opportunities that might lead the way to novel anthelminthic drugs.