Trajectories of Quality of Life after Hematopoietic Cell Transplantation: Secondary Analysis of Blood and Marrow Transplant Clinical Trials Network 0902 Data
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- 作者：Heather S.L. Jim1 ; heather.jim@moffitt.org" class="auth_mail" title="E-mail the corresponding author ; Steven K. Sutton2 ; Brent J. Small2 ; 3 ; Paul B. Jacobsen1 ; William A. Wood4 ; Jennifer M. Knight5 ; Navneet S. Majhail6 ; Karen L. Syrjala7 ; Stephanie J. Lee7
- 关键词：Hematopoietic stem cell transplantation ; Quality of life
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：22
- 期：11
- 页码：2077-2083
- 全文大小：700 K
文摘
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This secondary analysis of the Blood and Marrow Transplant Clinical Trials Network 0902 study examined the extent to which attrition results in biased estimates of patient quality of life and whether patients differ in terms of trajectories of quality of life in the first 6 months after transplantation
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Results indicated that attrition resulted in slightly biased overestimates of quality of life but the amount of overestimation remained stable over time
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Results also indicated that patients could be classified 3 distinct classes based on physical quality of life and 4 distinct classes based on mental quality of life
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Taken together, these findings help to better understand the course of recovery after hematopoietic cell transplantation