Noncoding RNAs: Regulators of the Mammalian Transcription Machinery
详细信息 查看全文
- 作者：Tess M. Eidem ; Jennifer F. Kugel ; jennifer.kugel@colorado.edu" class="auth_mail" title="E-mail the corresponding author ; James A. Goodrich ; james.goodrich@colorado.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：RNA polymerase II ; circular RNAs ; enhancer RNAs ; tethered RNAs ; divergent RNAs
- 刊名：Journal of Molecular Biology
- 出版年：2016
- 出版时间：19 June 2016
- 年：2016
- 卷：428
- 期：12
- 页码：2652-2659
- 全文大小：452 K
文摘
- •
Pol II transcription is regulated by ncRNAs.
- •
ncRNAs facilitate DNA looping and transcription factor recruitment.
- •
Promoter-proximal pausing by Pol II is influenced by ncRNAs.
- •
ncRNAs interact with Pol II to activate or inhibit transcription.
- •
Pol II uses its RNA-dependent RNA polymerase activity to regulate an ncRNA.