Biokinetics of food additive silica nanoparticles and their interactions with food components

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• 作者：Jeong-A Lee^a ; ¹ ; Mi-Kyung Kim^a ; ¹ ; Jae Ho Song^b ; ¹ ; Mi-Rae Jo^a ; Jin Yu^a ; Kyoung-Min Kim^b ; Young-Rok Kim^c ; ^{youngkim@khu.ac.kr} ; Jae-Min Oh^b ; ^{jaemin.oh@yonsei.ac.kr} ; Soo-Jin Choi^a ; ^{sjchoi@swu.ac.kr}
• 关键词：Oral absorption ; Size effect ; Silica nanoparticles ; Intestinal transport ; Interaction ; Food component ; Surface interaction
• 刊名：Colloids and Surfaces B: Biointerfaces
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：150
• 期：Complete
• 页码：384-392
• 全文大小：1619 K
• 卷排序：150

文摘

Biokinetics of food grade bulk and nano SiO2 particles were studied. Glucose and albumin interacted with SiO2 surface in a different manner. Oral absorption of nano SiO2 was greater than bulk counterpart. Oral absorption of nano SiO2 was affected by interaction with food components. Intestinal transport of nano SiO2 by M cells contributed to enhanced oral absorption.