Preferentially linear connection of gold nanoparticles in derivatization with phosphorothioate oligonucleotides
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- 作者：Jong-Yeob Kim ; Dong Hun Lee ; Seol Ji Kim ; Du-Jeon Jang
- 关键词：Artificial atoms ; Artificial molecules ; DNA ; Nanoconjunction ; Octet rule ; Self-assembly ; Silver
- 刊名：Journal of Colloid and Interface Science
- 出版年：2008
- 出版时间：15 October 2008
- 年：2008
- 卷：326
- 期：2
- 页码：387-391
- 全文大小：668 K
文摘
A gold nanosphere in water is considered to attain special stability in derivatization like an artificial atom when the octet rule is satisfied by forming four covalent bonds with two 5′-phosphorothioate-modified oligonucleotide molecules. Owing to this, the hybridization of two mutually complementary gold-bound oligonucleotides makes gold nanospheres preferentially connected linearly by duplexes to produce strands like linear artificial molecules. We have then fixated the linear strands of DNA-linked gold nanospheres by reducing Ag+ ion clusters immobilized around duplexes to show the absorption spectrum of silver-coated artificial-molecular nanorods.