High throughput screening of recombinant antibodies against infectious hematopoietic necrosis virus from a combinatorial antibody library
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- 作者：Li-Ming Xu 279463437@qq.com" class="auth_mail" title="E-mail the corresponding author ; Jing-Zhuang Zhao 422842454@qq.com" class="auth_mail" title="E-mail the corresponding author ; Miao Liu 446048847@qq.com" class="auth_mail" title="E-mail the corresponding author ; Yong-Sheng cao 375825652@qq.com" class="auth_mail" title="E-mail the corresponding author ; Jia-Sheng Yin xwsc20@tom.com" class="auth_mail" title="E-mail the corresponding author ; Hong-Bai Liu 112893129@qq.com" class="auth_mail" title="E-mail the corresponding author ; Tongyan-Lu ; lutongyan@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antibody library ; Antibody-antigen co-expression ; Bacterial display ; Glycoprotein ; Infectious hematopoietic necrosis virus
- 刊名：Aquaculture
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：460
- 期：Complete
- 页码：32-36
- 全文大小：1014 K
文摘
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A high throughput technique for screening of recombinant antibody was established.
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A panel of antibodies against Chinese infectious hematopoietic necrosis virus was isolated.
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The isolated antibody can be used as a universal diagnosis reagent for IHNV prevalent in China.
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The study provides a novel method for rapid development of antibodies to emerging diseases.