Screening for toxicity and resistance to paralytic shellfish toxin of shore crabs inhabiting at Leizhou peninsula, China

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• 作者：Huajuan Lin^a ; ^c ; ^{huajuanlin@vip.163.com} ; Yuji Nagashima^b ; ^{yujicd@kaiyodai.ac.jp} ; Peihong Jiang^a ; ^{jiangpeihongjph@163.com} ; Xiaoming Qin^c ; ^{qinchao0502@163.com} ; Yao Lu^a ; ^{luyao20009@126.com} ; Chaohua Zhang^a ; ^c ; ^{chz2382@126.com}
• 关键词：Shore crabs ; Paralytic shellfish toxin (PST) ; Toxicity ; Resistance to PST ; Toxicity neutralization effect ; Hemolymph ; Tetrodotoxin (TTX) ; Leizhou peninsula
• 刊名：Marine Environmental Research
• 出版年：2012
• 出版时间：July, 2012
• 年：2012
• 卷：78
• 期：Complete
• 页码：48-52
• 全文大小：223 K

文摘

The situation of the environment contaminated by paralytic shellfish toxin (PST) in Leizhou peninsula, China, has attracted more attention since seafood poisoning occurred occasionally. In this study, we examined the toxicities of shore crab Leptodius exaratus, Thalamita crenata and Metopograpsus latifrons by mouse assay, resistance to PST by lethal test injection with PST, and discussed the toxicity neutralization of their hemolymph. The results showed 12 % of shore crabs possessed toxicity of 4.3-4.4?MU/g. The 100 % lethal dose of PST for M.?latifrons was about 2 times of those for the other two crab species. The hemolymphs of the crabs were all able to neutralize PST and tetrodotoxin (TTX) toxicity in different extent. The above results indicate shore crabs at this area are exposed to an environment potentially contaminated with PST and/or TTX, and the toxicity neutralizing efficacy of their hemolymph directly affects their resistance to the toxins.