miRNA-216 and miRNA-499 target cyb561d2 in zebrafish in response to fipronil exposure
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- 作者：Yongyong Zhoua ; 1 ; Hannian Huangb ; 1 ; Kai Zhanga ; Xianfeng Dinga ; Longlue Jiaa ; Liang Yuc ; Guonian Zhuc ; Jiangfeng Guoa ; 603422689@qq.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：MicroRNA ; miR-155 ; miR-216b ; miR-499 ; cyb561d2 ; Toxicity ; Fipronil ; Zebrafish
- 刊名：Environmental Toxicology and Pharmacology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：45
- 期：Complete
- 页码：98-107
- 全文大小：1992 K
文摘
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miR-216b and miR-499 were interacted with cyb561d23′-untranslated regions (3′-UTR).
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miR-216b and miR-499 were downregulated upon stimulation of fipronil.
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The ectopic expression of miR-216b and miR-499 could regulate cyb561d2.
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miR-216b and miR-499 could be considered as potential biomarker for fipronil toxicity.