Ionic liquid-based negative pressure cavitation-assisted extraction of three main flavonoids from the pigeonpea roots and its pilot-scale application

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• 作者：Ming-Hui Duan ; Meng Luo ; Chun-Jian Zhao ; Wei Wang ; Yuan-Gang Zu ; Dong-Yang Zhang ; Xiao-hui Yao ; Yu-Jie Fu ; ^{yujie_fu2002@yahoo.com}
• 关键词：ILs-NPCE ; Ionic liquid-based negative pressure cavitation-assisted extraction ; ILs-HRE ; Ionic liquids heat-refluxing extraction ; ILs-UAE ; Ionic liquids ultrasound-assisted extraction ; BBD ; Box-Behnken design ; RSM ; response surface methodology
• 刊名：Separation and Purification Technology
• 出版年：2013
• 出版时间：2 April, 2013
• 年：2013
• 卷：107
• 期：Complete
• 页码：26-36
• 全文大小：1250 K

文摘

A new method, Ionic liquid-based negative pressure cavitation-assisted extraction (ILs-NPCE) was investigated to extract three main flavonoids genistin, genistein and apigenin from pigeonpea roots. The influential parameters of the ILs-NPCE were optimized by the single factor and the BBD (Box-Behnken design) experiments. [C₈mim]Br was used as the experiment ionic liquid, the optimal conditions were: temperature 74 ¡ãC, negative pressure ?0.07 MPa, liquid/solid ratio 20:1 mL/g, concentration 0.53 M and extraction time 15 min. The maximum extraction yields of genistin, genistein and apigenin were 0.482 ¡À 0.008, 0.496 ¡À 0.017 and 0.291 ¡À 0.015 mg/g, respectively. The extraction kinetics were also studied under the optimized conditions and it indicated that the ILs-NPCE showed much more advantages such as higher extraction yields, shorter time and more environmental friendly process than other methods. Moreover, this extraction method was also applied with pilot-scale extraction and their yields were 0.477 ¡À 0.013, 0.480 ¡À 0.014 and 0.271 ¡À 0.021 mg/g, respectively. Thus, it was indicated that the developed ILs-NPCE method could be an alternative method for natural compounds extraction in industry.