Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice
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- 作者：Mengyang Liua ; 1 ; Wenwen Zhanga ; 1 ; Xiaoju Lia ; Jihong Hanb ; c ; Yuanli Chenb ; d ; yuanli2014@nankai.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yajun Duanb ; c ; yajunduan@nankai.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Atherosclerosis ; Age ; Sex ; ABCA1 ; CD36
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：469
- 期：3
- 页码：456-462
- 全文大小：1482 K
文摘
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Atherosclerotic lesions in apoE-/- mice increase with ages and more in male mice.
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The increased lesions might be related to reduced hepatic cholesterol metabolism.
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Expression of Mϕ pro- and anti-atherogenic genes may make contribution to lesions.