A novel role of long non-coding RNAs in response to X-ray irradiation
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- 作者：Jihua Niea ; b ; f ; Chaojun Penga ; Weiwei Peib ; f ; Wei Zhua ; Shuyu Zhanga ; Han Caoa ; Xiaofei Qic ; Jian Tongb ; f ; tongjian@suda.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yang Jiaoa ; d ; e ; jiaoyang@suda.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：X-ray ; Long non-coding RNA (lncRNA) ; DNA damage ; p53 ; BRCA 1
- 刊名：Toxicology in Vitro
- 出版年：2015
- 出版时间：25 December 2015
- 年：2015
- 卷：30
- 期：1
- 页码：536-544
- 全文大小：1690 K
文摘
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The potential roles of lncRNAs in cellular response to radiation-induced DNA damage and oxidative stress were explored.
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A set of lncRNAs may response to IR damage in a dose-dependent manner.
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LncRNAs serve as novel indicators for radiation toxicity