A highly sensitive and selective impedimetric aptasensor for interleukin-17 receptor A
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- 作者：Hunho Joa ; 1 ; jhhsst@postech.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Seong-Kyeong Kima ; 1 ; ksk9089@postech.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Hyungjun Youna ; yhj1005@postech.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Heehyun Leeb ; delighthyun@postech.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Kwanghyun Leea ; kwanghyunlee@postech.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Jian Jeonga ; jian1031@postech.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Jihyun Mokc ; mokjihyun@postech.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Seung-Hyun Kimd ; kimsh@ajou.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Hae-Sim Parkd ; hspark@ajou.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Changill Bana ; ciban@postech.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：IL-17RA ; Aptamer ; Impedance spectroscopy ; Biosensor ; Autoimmune disease
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：81
- 期：Complete
- 页码：80-86
- 全文大小：1714 K
文摘
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The design of an aptasensor for IL-17RA.
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A wide dynamic range of 10–10,000 pg/mL and a detection limit of 2.13 pg/mL.
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Robust sensitivity and selectivity of impedimetric biosensor.
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Successful detection of the differentiated HL-60 cells expressing IL-17RA.
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Great applicability towards clinical samples.