Triphenyltin degradation and proteomic response by an engineered Escherichia coli expressing cytochrome P450 enzyme

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• 作者：Wenying Yi^a ; Kunliang Yang^a ; Jinshao Ye^a ; ^b ; ^{jinshaoye@lbl.gov} ; ^{folaye@126.com} ; Yan Long^a ; Jing Ke^b ; Huase Ou^a
• 关键词：Organotin ; Bacillus thuringiensis ; Gene clone ; Proteomics ; ITRAQ
• 刊名：Ecotoxicology and Environmental Safety
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：137
• 期：Complete
• 页码：29-34
• 全文大小：544 K
• 卷排序：137

文摘

P450 could cleave carbon-metal bonds. PntB regulated electron transfer from NADH to P450 during TPT degradation process. Up-regulated protein network was related to transport, energy synthesis, cell division. Up-regulated proteins were related to amino acid synthesis. TPT did not significantly depressed cellular metabolism at a protein network level.