Studies on the characteristic and activity of low-molecular fragments from zymosan
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- 作者：Yang Gao ; Ruizhi Jiang ; Jing Qie ; Yinghong Chen ; Duoduo Xu ; Wei Liu ; Qipin Gao
- 关键词：Zymosan ; Glycosidic linkage ; Anti-chronic atrophic gastritis activity
- 刊名：Carbohydrate Polymers
- 出版年：2012
- 出版时间：6 November, 2012
- 年：2012
- 卷：90
- 期：4
- 页码：1411-1414
- 全文大小：377 K
文摘
Zymosan was hydrolysed with HCl and fractionated by ultrafiltration and dialysis to obtain water-soluble fragments A, B and C. Physical and chemical analyses showed that these fractions are composed primarily of glucose and have molecular weights of 8 kDa, 5 kDa and 2 kDa, respectively. A glycosidic linkage analysis indicated that they are mainly composed of ¦Â-1,3-glucans. Fragment A, which has the highest molecular weight, contains approximately 30 % ¦Â-1,6-linked glucans, but fragment C is almost entirely composed of linear ¦Â-1,3-glucan chains. The anti-chronic atrophic gastritis activity experiments showed that fragment A has significant activity, the activity of zymosan is quite low and the activities of fragments B and C are in between those of fragment A and zymosan.