Behavioral characterization of CD36 knockout mice with SHIRPA primary screen
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- 作者：Shuxiao Zhangc ; d ; e ; 1 ; Wei Wanga ; c ; d ; 1 ; Juan Lib ; c ; d ; 1 ; Ke Chengb ; c ; d ; 1 ; Jingjing Zhouc ; d ; Dan Zhub ; Deyu Yanga ; d ; Zihong Liangc ; d ; f ; Liang Fanga ; d ; Li Liaoc ; d ; e ; Peng Xiea ; b ; c ; d ; xiepeng58@21cn.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：CD36&minus ; /&minus ; mice ; CD36 knockout mice ; SPT ; sucrose preference test ; SP ; sucrose preference ; OFT ; open-field test ; EPM ; elevated plus-maze ; FST ; forced swimming test
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：15 February 2016
- 年：2016
- 卷：299
- 期：Complete
- 页码：90-96
- 全文大小：998 K
文摘
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SHIRPA primary screen were successfully applied to CD36−/− mice and C57BL/6J mice.
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CD36−/− mice displayed increased aggression and locomotor activity in SHIRPA primary screen.
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Multiple neuropsychiatric diseases (mainly depression and anxiety) related behavioral tests were conducted in CD36−/− mice and C57BL/6J mice.
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CD36−/− mice showed increased anxiety-like behavior.