Involvement of water channel Aquaporin 5 in H₂S-induced pulmonary edema

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• 作者：Chunyang Xu^a ; ¹ ; Lei Jiang^a ; ¹ ; Yuxia Zou^b ; Jingjing Xing^a ; Hao Sun^a ; Baoli Zhu^c ; Hengdong Zhang^c ; Jun Wang^b ; ^{wangjun@njmu.edu.cn} ; Jinsong Zhang^a ; ^{zhangjsojz@163.com}
• 关键词：Hydrogen sulfide ; Aquaporin 5 ; ERK1/2 ; JNK ; p38 MAPK ; Pulmonary edema
• 刊名：Environmental Toxicology and Pharmacology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：49
• 期：Complete
• 页码：202-211
• 全文大小：3583 K
• 卷排序：49

文摘

H2S significantly contributed to lung injury. H2S obviously increased AQP5 expression in A549 cell line and mouse lung tissues. MAPK signaling pathways were involved in H2S-induced AQP5 expression