The expression of human β-defensins (hBD-1, hBD-2, hBD-3, hBD-4) in gingival epithelia
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HBD-4was first detected both in chronic inflamed and healthy gingiva.

The mRNA relative expression of four β-defensins were analyzed in same sample.

The peptide expression of hBD-4 was observed in the nucleus and cytoplasm, hBD-1, hBD-2 and hBD-3 were observed in the cytoplasm.

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