Decreased c-rel activation contributes to aberrant interleukin-2 expression in CD4+T cells of aged rats
详细信息 查看全文
- 作者：Zhangbin Gonga ; 1 ; Te Liub ; 1 ; Yinhan Wanc ; Zhifeng Hanga ; Xiaopeng Tongd ; e ; Bei Zhange ; Haozheng Yangf ; Xueli Zhanga ; Lina Zhanga ; Guoqin Jina ; jinguoqin8405@126.com" class="auth_mail ; zhangbingong@126.com" class="auth_mail
- 关键词：Aging ; Interleukin-2 ; C-rel ; Transcription ; Immunosenescence
- 刊名：Molecular Immunology
- 出版年：September 2014
- 年：2014
- 卷：61
- 期：1
- 页码：1-6
- 全文大小：1079 K
文摘
- class="listitem" id="list_lis0005">
- class="label">•
IL-2 expression declined in rat CD4+T cells of various ages.
- class="label">•
C-rel nuclear translocation declined in the restimulated aged rat CD4+T cells.
- class="label">•
C-rel binding on the IL-2 promoter region declined in the aged rat CD4+T cells.