The hippocampus participates in a pharmacological rat model of absence seizures
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- 作者：Justin Arcaroa ; b ; c ; jarcaro@uwo.ca" class="auth_mail" title="E-mail the corresponding author ; Jingyi Mab ; jma2@uwo.ca" class="auth_mail" title="E-mail the corresponding author ; Liangwei Chub ; lchu46@uwo.ca" class="auth_mail" title="E-mail the corresponding author ; MinChing Kuob ; snowicek@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Seyed M. Mirsattaria ; c ; Seyed.Mirsattari@lhsc.on.ca" class="auth_mail" title="E-mail the corresponding author ; L. Stan Leunga ; b ; sleung@uwo.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Absence seizure ; Thalamocortical network ; Gamma-butyrolactone (GBL) ; Synchronization ; Local field potentials ; Hippocampus
- 刊名：Epilepsy Research
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：120
- 期：Complete
- 页码：79-90
- 全文大小：3592 K
文摘
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Gamma-butyrolactone induced absence-like, 2.5–6 Hz paroxysmal discharges in LE rats.
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Thalamocortical discharges entrained hippocampal potential and units.
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Inactivation of the hippocampus hastened the slowing of discharges.
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Hippocampal entrainment may contribute to cognitive deficits during absence seizure.