Fluoride caused thyroid endocrine disruption in male zebrafish (Danio rerio)
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- 作者：Chen Jianjie1 ; Xue Wenjuan1 ; Cao Jinling ; caojinling7928@aliyun.com" class="auth_mail" title="E-mail the corresponding author ; Song Jie ; Jia Ruhui ; Li Meiyan
- 关键词：CRH ; corticotrophin-releasing hormone ; THS ; thyroid-stimulating hormone ; TG ; thyroglobulin ; NIS ; sodium iodide symporter ; DIO1 ; iodothyronine I ; DIO2 ; iodothyronineII ; TRα ; thyroid hormone receptor alpha ; TRβ ; thyroid hormone receptor beta ; UGT1ab ; UDP glucuronosyltransferase 1 family a ; b ; TTR ; transthyretin
- 刊名：Aquatic Toxicology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：171
- 期：Complete
- 页码：48-58
- 全文大小：2194 K
文摘
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Fluoride inhibited the growth of male zebrafish.
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Fluoride injured the histological structure of thyroid in male zebrafish.
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Fluoride changed T3 and T4 levels, and genes transcriptions involved in HPT axis.