Fluoride exposure changed the structure and the expressions of Y chromosome related genes in testes of mice
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- 作者：Jinling Cao1 ; Yan Chen1 ; Jianjie Chen ; Hanghang Yan ; Meiyan Li ; Jundong Wang ; wangjd53@outlook.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Fluoride ; Testes ; Y chromosome microdeletion genes ; Spermatogenesis ; HSF2
- 刊名：Chemosphere
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：161
- 期：Complete
- 页码：292-299
- 全文大小：1513 K
文摘
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F changed histological structure of testes, reduced sperm quality.
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F reduced the testosterone contents of serum and testis.
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F decreased the expressions of Sly, HSF2 and Ssty2.
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Depressed HSF2 level resulted in the down-regulation of Ssty2 and Sly expression.
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F affects spermatogenesis and decreases levels of Y chromosome microdeletion genes.