Data on PRRSV infection promoted the subtype of porcine dendritic cells from mDCs to pDCs in vivo

详细信息    查看全文

• 作者：Jinling Liu^a ; ^{Ljlfree@sina.com} ; Shu Wei^b ; ¹ ; Lixia Liu^a ; ¹ ; Lihui Yu^a ; Chunyan Wang^c ; Yujun Zhao^a ; Fengping Shan^d ; Guoshun Shen^a ;
• 关键词：PRRSV ; Subtype ; Dendritic cells
• 刊名：Data in Brief
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：9
• 期：Complete
• 页码：155-158
• 全文大小：1852 K
• 卷排序：9

文摘

The related study has confirmed that porcine reproductive and respiratory syndrome virus (PRRSV) infection may impair mature states of DCs can lead to suboptimal adaptive immune response (“The role of porcine reproductive and respiratory syndrome virus infection in immunephenotype and Th1/Th2 balance of dendritic cells” (Jinling Liu, We Shu, Liaxia Liu et al., 2016) [1]). In this data article,the porcine dendritic cells (DCs) isolated from porcine peripheral blood and spleen were collected after infection with PRRSV, then the characteristics of the subset differentiation of DCs were analyzed with FACS Calibur Cytometer and fluorescence microscope respectively. This data is an important foundation for further investigation into immune suppression by PRRSV infection, and that, it also provides new data for the development of potential antiviral therapies based on DCs and PRRS vaccines.