Preparation and properties of hydrogels based on PEG and isosorbide building blocks with phosphate linkages
详细信息 查看全文
- 作者：Jia Cheng ; Pei Zhang ; Tao Liu ; Jinwen Zhang ; jwzhang@wsu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hydrogel ; Green epoxy ; Monophosphate ester
- 刊名：Polymer
- 出版年：2015
- 出版时间：5 November 2015
- 年：2015
- 卷：78
- 期：Complete
- 页码：212-218
- 全文大小：1470 K
文摘
- •
PEG monophosphate (PEGP) and isosorbide diglycidyl ether (IDE) were synthesized.
- •
New hydrogels with phosphate linkages were prepared by reacting IDE with PEGP.
- •
The crosslinking reaction occurred at room temperature without catalyst and solvent.
- •
The hydrogels exhibited characteristic swelling and degradation.
- •
Drug release of the hydrogel was influenced by the chain length of PEG moiety.