Scalable microcarrier-based manufacturing of mesenchymal stem/stromal cells
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- 作者：Antó ; nio M. de Soure ; Ana Fernandes-Platzgummer ; Clá ; udia L. da Silva ; Joaquim M.S. Cabral<sup> ; sup><sup>joaquim.cabral@tecnico.ulisboa.pt" class="auth_mail" title="E-mail the corresponding authorsup>
- 关键词：Mesenchymal stem/stromal cells ; Ex vivo expansion ; Microcarriers ; Serum/xenogeneic-free ; Cell manufacturing ; Bioreactors
- 刊名：Journal of Biotechnology
- 出版年：2016
- 出版时间：20 October 2016
- 年：2016
- 卷：236
- 期：Complete
- 页码：88-109
- 全文大小：2191 K
文摘
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Comprehensive overview on the manufacturing of human mesenchymal stem/stromal cells.
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Bioprocess engineering approaches combining bioreactors with microcarrier technology for the expansion of mesenchymal stem/stromal cells.
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Current and future mesenchymal stem/stromal cell manufacturing challenges.