Validation of the FAM19A4/mir124-2 DNA methylation test for both lavage- and brush-based self-samples to detect cervical (pre)cancer in HPV-positive women
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- 作者：Lise M.A. De Stroopera ; l.destrooper@vumc.nl" class="auth_mail" title="E-mail the corresponding author ; Viola M.J. Verhoefa ; v.verhoef@vumc.nl" class="auth_mail" title="E-mail the corresponding author ; Johannes Berkhofb ; h.berkhof@vumc.nl" class="auth_mail" title="E-mail the corresponding author ; Albertus T. Hesselinkc ; b.hesselink@vumc.nl" class="auth_mail" title="E-mail the corresponding author ; Helena M.E. de Bruina ; hmedebruin@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Folkert J. van Kemenaded ; f.vankemenade@erasmusmc.nl" class="auth_mail" title="E-mail the corresponding author ; Remko P. Bosgraafe ; Remko.Bosgraaf@radboudumc.nl" class="auth_mail" title="E-mail the corresponding author ; Ruud L.M. Bekkerse ; Ruud.Bekkers@radboudumc.nl" class="auth_mail" title="E-mail the corresponding author ; Leon F.A.G. Massugere ; Leon.Massuger@radboudumc.nl" class="auth_mail" title="E-mail the corresponding author ; Willem J.G. Melchersf ; Willem.Melchers@radboudumc.nl" class="auth_mail" title="E-mail the corresponding author ; Renske D.M. Steenbergena ; r.steenbergen@vumc.nl" class="auth_mail" title="E-mail the corresponding author ; Peter J.F. Snijdersa ; pjf.snijders@vumc.nl" class="auth_mail" title="E-mail the corresponding author ; Chris J.L.M. Meijera ; cjlm.meijer@vumc.nl" class="auth_mail" title="E-mail the corresponding author ; Danië ; lle A.M. Heidemana ; dam.heideman@vumc.nl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Human papillomavirus ; Self-sampling ; Reflex test ; Cervical cancer ; Molecular screening ; DNA methylation ; HPV16/18 genotyping
- 刊名：Gynecologic Oncology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：141
- 期：2
- 页码：341-347
- 全文大小：517 K
文摘
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FAM19A4/mir124-2 triage of HPV-positive self-samples is a feasible and promising tool
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FAM19A4/mir124-2 analysis identifies HPV-positive women at risk of cervical cancer.
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FAM19A4/mir124-2 analysis performs equally well in lavage and brush self-samples.
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Further validation of HPV self-sampling with FAM19A4/mir124-2 triage is warranted