Detection of bowel inflammation with fused DWI/T2 images versus contrast-enhanced images in pediatric MR enterography with histopathologic correlation

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• 作者：Eric C. Ehman^a ; ^{eric.ehman@ucsf.edu" class="auth_mail" title="E-mail the corresponding author} ; Andrew S. Phelps^b ; ¹ ; ^{andrew.phelps@ucsf.edu" class="auth_mail" title="E-mail the corresponding author} ; Michael A. Ohliger^a ; ² ; ^{michael.ohliger@ucsf.edu" class="auth_mail" title="E-mail the corresponding author} ; Sue J. Rhee^c ; ³ ; ^{sue.rhee@ucsf.edu" class="auth_mail" title="E-mail the corresponding author} ; John D. MacKenzie^b ; ² ; ^{john.mackenzie@ucsf.edu" class="auth_mail" title="E-mail the corresponding author} ; Jesse L. Courtier^b ; ² ; ^{jesse.courtier@ucsf.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：MRI ; Enterography ; Diffusion-weighted imaging ; Pediatric
• 刊名：Clinical Imaging
• 出版年：2016
• 出版时间：November-December 2016
• 年：2016
• 卷：40
• 期：6
• 页码：1135-1139
• 全文大小：721 K

文摘

To evaluate the fused, colorized diffusion weighted imaging (DWI) and anatomic T2 images compared to routine contrast-enhanced T1 images at pediatric magnetic resonance enterography (MRE).

Methods

Fused, colorized DWI/T2 images were created from patients with magnetic resonance enterography (MRE) and colonoscopy/biopsy. Radiologists noted inflammation in five bowel segments (terminal ileum–rectosigmoid colon) on postcontrast images and DWI/T2 images. Test characteristics and agreement were calculated.

Results

For 20 patients, sensitivity/specificity/positive predictive value (PPV)/negative predictive value (NPV) were 0.53/0.90/0.77/0.76 for DWI/T2 and 0.45/0.90/0.72/0.73 for postcontrast images. Intraobserver agreement was ҡ=0.45–0.73. Interobserver agreement was ҡ=0.53 for DWI/T2 and ҡ=0.63 for postcontrast images.

Conclusion

DWI/T2 images are similar in sensitivity/specificity to contrast-enhanced images and with moderate intra/interobserver reliability.