Coping Effectively With Heart Failure (COPE-HF): Design and Rationale of a Telephone-Based Coping Skills Intervention

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• 作者：Andrew Sherwood PhD¹ ; ^{sherw002@mc.duke.edu} ; Christopher M. O’ ; Connor MD¹ ; Faye S. Routledge RN ; PhD¹ ; Alan L. Hinderliter MD² ; Lana L. Watkins PhD¹ ; Michael A. Babyak PhD¹ ; Gary G. Koch PhD² ; Kirkwood F. Adams Jr. MD² ; Carla Sueta Dupree MD ; PhD² ; Patricia P. Chang MD ; MHS² ; Benson M. Hoffman PhD¹ ; Julie Johnson PA¹ ; Margaret Bowers NP¹ ; Kristy S. Johnson MPH¹ ; James A. Blumenthal PhD¹
• 关键词：Self-management ; biomarkers ; quality of life ; depression
• 刊名：Journal of Cardiac Failure
• 出版年：2011
• 出版时间：March 2011
• 年：2011
• 卷：17
• 期：3
• 页码：201-207
• 全文大小：205 K

文摘

Background

Coping Effectively with Heart Failure (COPE-HF) is an ongoing randomized clinical trial funded by the National Institutes of Health to evaluate if a coping skills training (CST) intervention will result in improved health status and quality of life as well as reduced mortality and hospitalizations compared with a heart failure education (HFE) intervention.

Methods and Results

Two hundred heart failure (HF) patients recruited from the Duke University Medical Center and the University of North Carolina Hospital system will be randomized to a CST intervention (16 weekly 30-minute telephone counseling sessions including motivational interviewing and individually tailored cognitive behavioral therapy) or to an HFE intervention (16 weekly 30-minute telephone sessions including education and symptom monitoring). Primary outcomes will include postintervention effects on HF biomarkers (B-type natriuretic peptide, ejection fraction) and quality of life, as well as long-term clinical outcomes (hospitalizations and death). Secondary analyses will include an evaluation of treatment effects across subpopulations, and potential mechanisms by which CST may improve clinical outcomes.

Conclusions

COPE-HF is a proof-of-concept study that should provide important insights into the health benefits of a CST intervention designed to enhance HF self-management, improve health behaviors, and reduce psychologic distress.