Change in Pain and Quality of Life Among Women Enrolled in a Trial Examining the Use of Narrow Band Imaging During Laparoscopic Surgery for Suspected Endometriosis

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• 作者：Lisa Gallicchio ; PhD^a ; ^b ; ^{lisagallicchio@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Kathy J. Helzlsouer ; MD ; MHS^a ; ^c ; Kevin M. Audlin ; MD^a ; Charles Miller ; MD^d ; ^e ; Ryan MacDonald ; PhD^a ; Mary Johnston ; RNFA ; BSN ; CNOR^d ; Fermin F. Barrueto ; MD^a
• 关键词：Endometriosis ; Laparoscopy ; Narrow band imaging ; Pain ; Quality of life
• 刊名：Journal of Minimally Invasive Gynecology
• 出版年：2015
• 出版时间：November-December 2015
• 年：2015
• 卷：22
• 期：7
• 页码：1208-1214
• 全文大小：382 K

文摘

To examine whether the addition of narrow band imaging (NBI) to traditional white light imaging during laparoscopic surgery impacts pain and quality of life (QOL) at 3 and 6 months after surgery among women with suspected endometriosis and/or infertility.

Design

A randomized controlled trial (Canadian Task Force classification level I).

Setting

The trial was conducted in 2 medical centers.

Patients

From October 2011 to November 2013, 167 patients undergoing laparoscopic examination for suspected endometriosis and/or infertility were recruited. The analytic study sample includes 148 patients with pain and QOL outcome data.

Interventions

Patients were randomized in a 3:1 ratio to receive white light imaging followed by NBI (WL/NBI) or white light imaging only (WL/WL).

Measurements and Main Results

Questionnaires were administered at baseline and at 3- and 6-month follow-up time points. Average and most severe pain at each time point were assessed using a 10-cm visual analog scale. QOL was measured using the Endometriosis Health Profile-30. Baseline characteristics were similar for the study groups. The WL/NBI and WL/WL groups had similar reductions in pain at 3 and 6 months. In addition, QOL improved similarly for both the WL/NBI and WL/WL groups at 3 and 6 months.

Conclusion

Laparoscopic surgery for suspected endometriosis is associated with a reduction in pain and an improvement in QOL. The differences in pain reduction and QOL improvement, which are noted at 3 months and remain stable at 6 months after surgery, are similar for those undergoing surgery with WL/NBI compared with those undergoing surgery under traditional white light conditions.