Spectroscopy markers of suicidal risk and mental pain in depressed patients

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• 作者：Fabrice Jollant ; M.D. Ph.D.^a ; ^b ; ^{fabrice.jollant@mcgill.ca} ; Jamie Near ; Ph.D.^c ; Gustavo Turecki ; M.D. Ph.D.^a ; Sté ; phane Richard-Devantoy ; M.D. Ph.D.^a
• 关键词：Suicide attempt ; Depression ; Spectroscopy ; Prefrontal cortex ; Psychological pain
• 刊名：Progress in Neuro-Psychopharmacology and Biological Psychiatry
• 出版年：2017
• 出版时间：6 February 2017
• 年：2017
• 卷：73
• 期：Complete
• 页码：64-71
• 全文大小：626 K
• 卷排序：73

文摘

Nine metabolites were measured with spectroscopy in right dorsal prefrontal cortex. Suicide attempters did not differ from controls after correction. NAA levels were negatively correlated with psychological pain. Choline levels were positively correlated with suicidal ideas. Glial and neuronal impairments may underlie cardinal signs of the suicidal crisis.