The number needed to treat (NNT) can be adjusted for bias when the outcome is measured with error

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• 作者：Marschner ; Ian C. ; Emberson ; Jonathan ; Irwig ; Les ; Walter ; Stephen D.
• 关键词：Bias ; Measurement error ; Number needed to treat ; Randomized controlled trial
• 刊名：Journal of Clinical Epidemiology
• 出版年：2004
• 出版时间：December, 2004
• 年：2004
• 卷：57
• 期：12
• 页码：1244-1252
• 全文大小：574 K

文摘

We consider the number needed to treat (NNT) when the event of interest is defined by dichotomizing a continuous response at a threshold level. If the response is measured with error, the resulting NNT is biased. We consider methods to reduce this bias.