Respiratory muscle training (RMT) in late-onset Pompe disease (LOPD): Effects of training and detraining
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- 作者：Harrison N. Jonesa ; harrison.jones@duke.edu" class="auth_mail" title="E-mail the corresponding author ; Kelly D. Crispb ; kelly.crisp@duke.edu" class="auth_mail" title="E-mail the corresponding author ; Randall R. Robeyc ; rrr7w@eservices.virginia.edu" class="auth_mail" title="E-mail the corresponding author ; Laura E. Cased ; laura.case@duke.edu" class="auth_mail" title="E-mail the corresponding author ; Richard M. Kravitze ; richard.kravitz@duke.edu" class="auth_mail" title="E-mail the corresponding author ; Priya S. Kishnanif ; priya.kishnani@duke.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Glycogen storage disease type II ; Skeletal muscle ; Exercise ; Rehabilitation ; Breathing exercises
- 刊名：Molecular Genetics and Metabolism
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：117
- 期：2
- 页码：120-128
- 全文大小：381 K
文摘
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Inspiratory/expiratory muscle weakness is common in late-onset Pompe disease (LOPD).
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Respiratory muscle training (RMT) is one approach to target respiratory weakness.
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12-week RMT program was conducted in 8 LOPD subjects using single-subject design
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Large to very large strength increases from pretest to posttest
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Strength increases were generally maintained over 3-month RMT withdrawal.