Protective effect of acetyl-l-carnitine on propofol-induced toxicity in embryonic neural stem cells

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• 作者：Fang Liu^a ; ^{Fang.liu@fda.hhs.gov" class="auth_mail} ; Shuo W. Rainosek^b ; Natalya Sadovova^c ; Charles M. Fogle^a ; Tucker A. Patterson^a ; Joseph P. Hanig^d ; Merle G. Paule^a ; William Slikker Jr.^e ; Cheng Wang^a ; ^{Cheng.wang@fda.hhs.gov" class="auth_mail}
• 关键词：CNS ; central nervous system ; GABA ; gamma-aminobutyric acid ; l-Ca ; acetyl-l-carnitine ; DMEM ; Dulbecco's modified Eagle's medium ; ELISA ; enzyme-linked immunosorbent assay ; TUNEL ; terminal deoxynucleotidyl transferase (TdT)-mediated deoxy-uridine triphosphate (dUTP) nick end labeling ; MTT ; 3-(4 ; 5-dimethylthiazole-2-yl)-2 ; 5-diphenyltetrazolium bromide ; LDH ; lactate dehydrogenase
• 刊名：Neurotoxicology
• 出版年：May 2014
• 年：2014
• 卷：42
• 期：Complete
• 页码：49-57
• 全文大小：2265 K

文摘

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d="par0005">Propofol reduced neural stem cell viability.

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d="par0010">Propofol reduced neural stem cell proliferation.

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d="par0015">Acetyl-l-carnitine attenuates propofol's adverse effects.

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