Imbalanced spontaneous brain activity in orbitofrontal-insular circuits in individuals with cognitive vulnerability to depression
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文摘

CVD subjects had reduced ALFF in the bilateral OFC and increased ALFF in the bilateral IC during resting-state.

CSQ scores in CVD subjects did correlate with ALFF values in the left IC.

Abnormal ALFF in orbitofrontal-insular circuits might represent a trait-related marker of vulnerability to depression.

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