ToF-SIMS study on the effects of different calcium sources on silica/纬-PGA hybrid synthesis.
Use of DMSO to dissolve free acid form of 纬-PGA is not ideal for hybrid synthesis.
Using calcium salt form of polymer can obtain homogeneous hybrids but reduces coupling.
Ionic cross-linking using DMC to synthesize silica/纬-PGA hybrids is proposed.
DMC should be added at the onset of the hybrid synthesis reaction.