Interleukin 23 regulates the functions of human decidual immune cells during early pregnancy
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- 作者：Jun-Ying Cai caijunying2012@126.com" class="auth_mail" title="E-mail the corresponding author ; Mu-Jun Li ; lmj20051699@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Human decidual immune cells ; Treg cells ; Th17 cells ; IL-23 ; IL-17 ; STAT3
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：469
- 期：3
- 页码：340-344
- 全文大小：607 K
文摘
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Human IL-23 and anti-IL-23 can affect the balance of Treg/Th17 from DICs.
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IL-23 increase the levels of pSTAT3, anti-IL-23 decrease the pSTAT3 and IL-23R.
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IL-23 increase the proinflammatory cytokines and have a rising trend with the time.