Characterization of ion channels on subesophageal ganglion neurons from Chinese tarantula Ornithoctonus huwena: Exploring the myth of the spider insensitive to its venom
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- 作者：Meichun Denga ; c ; 1 ; dengmch@csu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Zhaotun Hub ; c ; 1 ; huzhaotun@163.com" class="auth_mail" title="E-mail the corresponding author ; Tianfu Caic ; Kai Liuc ; Wenfang Wua ; Xuan Luoc ; Liping Jiangd ; Meichi Wangc ; Jing Yangc ; Yucheng Xiaoc ; Songping Liangc ; liangsp@hunnu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Chinese tarantula ; Toxin ; Adaptive insensitivity ; Calcium channel ; Potassium channel ; Sodium channel ; Whole-cell
- 刊名：Toxicon
- 出版年：2016
- 出版时间：15 September 2016
- 年：2016
- 卷：120
- 期：Complete
- 页码：61-68
- 全文大小：1489 K
文摘
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Tarantula neurons express at least voltage-gated calcium channels, TTX-sensitive sodium channels, and potassium channels.
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The tarantula ion channels exhibit pharmacological properties similar to mammalian subtypes.
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The findings provide important evidence for ion channels from spiders having an evolution as self-defense and prey mechanism.