Kinetic resolution of (R,S)-α-tetralol catalyzed by crosslinked Candida antarctica lipase B enzyme supported on mesocellular foam: A nanoscale enzyme reactor approach
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- 作者：Manoj P. Kamble
- 关键词：C. antarctica lipase B ; Mesoporous microcellular foam (MCF) ; Enantio-selectivity ; α-tetralol ; Enzyme kinetics
- 刊名：Journal of Molecular Catalysis B: Enzymatic
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：132
- 期：Complete
- 页码：61-66
- 全文大小：730 K
文摘
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- <p id="par0005">Nanoscale enzyme reactors of C. antarctica lipase B were synthesized on mesoporous microcellular foam.p>
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- <p id="par0010">CALB/MCF catalyzed kinetic resolution of (R,S)-α-tetralol in organic media.p>
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- <p id="par0015">A conversion of 43.7% with 100% selectivity for (R)-α-tetralol (eep >99.9%) was obtained at 50 °C in 24 h, using CALB/MCF.p>
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- <p id="par0020">Developed biocatalyst can be readily recoverd and reused up to three cycles.p>