Renoprotective effect of diosgenin in streptozotocin induced diabetic rats
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- 作者：Divya M. Kanchan ; Gauresh S. Somani ; Vaibhavi V. Peshattiwar ; Aakruti A. Kaikini ; Sadhana Sathaye ; sadhanasathaye@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Diabetes ; Diosgenin ; Kidney ; Oxidative stress ; Serum advanced glycation end-products
- 刊名：Pharmacological Reports
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：68
- 期：2
- 页码：370-377
- 全文大小：2547 K
文摘
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Diabetes associated kidney injury was studied in streptozotocin induced male Wistar rats.
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Diogenin, a steroidal sapogenin, treatment was given for 28 days.
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Diosgenin protected the kidney from diabetic injury through suppression of oxidative stress and inflammatory response.
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Diosgenin demonstrated anti-glycating properties.
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Diosgenin improved the renal function in diabetic rats.