Large particulate allergens can elicit mast cell-mediated anaphylaxis without exit from blood vessels as efficiently as do small soluble allergens
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文摘

Large particulate allergens can induce anaphylaxis without exit from blood vessels.

Particulate allergen-elicited anaphylaxis is dependent on IgE and mast cells.

Intravascular allergens interact with perivascular mast cells across the vessel wall.

These findings may explain why anaphylaxis occurs shortly after allergen challenge.

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