Cancer stem cells: a challenging paradigm for designing targeted drug therapies
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- 作者：Ishaq N. Khan1 ; 2 ; 3Author Vitae ; Saleh Al-Karim1 ; 4Author Vitae ; Roop S. Bora1 ; 5 ; 6 ; Adeel G. Chaudhary2 ; 3 ; Kulvinder S. Saini1 ; 5 ; 6 ; kulvin.singh@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; ksaini@kau.edu.sa" class="auth_mail" title="E-mail the corresponding author ; sainikulvinder@gmail.com" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 刊名：Drug Discovery Today
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：20
- 期：10
- 页码：1205-1216
- 全文大小：1173 K
文摘
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New drug discovery and molecules in clinical development against cancer stem cells.
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Surface marker, transcription factors and signal transduction pathways in CSCs.
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RNAi, miRNA, biologics, vaccines, etc. for targeting therapeutics against CSCs.
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Plasticity model remains the most attractive hypothesis for designing targeted therapies.