Neuropsychological and psychiatric changes after deep brain stimulation for Parkinson's disease: a randomised, multicentre study
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- 作者：Karsten Witt ; Christine Daniels ; Julia Reiff ; Paul Krack ; Jens Volkmann ; Markus O Pinsker ; Martin Krause ; Volker Tronnier ; Manja Kloss ; Alfons Schnitzler ; Lars Wojtecki ; Kai Bö ; tzel ; Adrian Danek
- 关键词：International operations ; Aluminium protection ; Ballistic tests ; Numerical simulations ; Design
- 刊名：Lancet Neurology
- 出版年：2008
- 出版时间：July 2008
- 年：2008
- 卷：7
- 期：7
- 页码：605-614
- 全文大小：167 K
文摘
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) reduces motor symptoms in patients with Parkinson's disease (PD) and improves their quality of life; however, the effect of DBS on cognitive functions and its psychiatric side-effects are still controversial. To assess the neuropsychiatric consequences of DBS in patients with PD we did an ancillary protocol as part of a randomised study that compared DBS with the best medical treatment.