Altered gene expression of H19 and IGF2 in placentas from ART pregnancies
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- 作者：Sina Sakian1 ; Kenny Louie1 ; Edgar Chan Wong ; Jon Havelock ; Sonya Kashyap ; Timothy Rowe ; Beth Taylor ; Sai Ma ; sai@mail.ubc.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Assisted reproductive technology ; Imprinted genes ; Placenta ; DNA Methylation ; Gene expression
- 刊名：Placenta
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：36
- 期：10
- 页码：1100-1105
- 全文大小：332 K
文摘
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IVF and ICSI derived placentas show altered H19 and IGF2 expression.
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ICR1 DNA methylation is similar in IVF, ICSI, and naturally conceived placentas.
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We show an inverse relationship in H19 and IGF2 expression in placentas.
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H19 and IGF2 expression may not be entirely associated with ICR1 DNA methylation.