Diagnostic utility of new immunoassays for the cardiac markers cTnI, myoglobin and CK-MB mass

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• 作者：Michael Weber ; Matthias Rau ; Katharina Madlener ; Albrecht Elsaesser ; Dragic Bankovic ; Veselin Mitrovic and Christian Hamm
• 刊名：Clinical Biochemistry
• 出版年：2005
• 出版时间：November 2005
• 年：2005
• 卷：38
• 期：11
• 页码：1027-1030
• 全文大小：159 K

文摘

Objectives:

We investigated the diagnostic value of a new system, the Innotrac Aio!™ immunoassays for troponin, myoglobin and CK-MB, in 270 samples from patients with ACS, after bypass surgery (CABG) or with stable heart failure in comparison to the respective Roche assays.

Results:

The values of the cardiac markers assessed by the respective assays correlated (cTnT/cTnI Rho = 0.94, myoglobin Rho = 0.87, CK-MB Rho = 0.84). If values were dichotomised, we found a high concordance of test positive and negative classified patients by troponins with the respective assays.

Conclusion:

There is strong evidence that the Innotrac Aio!™ system for cTnI measurement can be used reliably.