Relative differences in resting-state brain connectivity associated with long term intensive lifestyle intervention
详细信息 查看全文
- 作者：Ramon Casanova ; PhDa ; casanova@wakehealth.edu" class="auth_mail" title="E-mail the corresponding author ; Satoru Hayasakab ; Hayasaka@utexas.edu" class="auth_mail" title="E-mail the corresponding author ; Santiago Saldanaa ; ssaldana@wakehealth.edu" class="auth_mail" title="E-mail the corresponding author ; Nick R. Bryanc ; r.nick.bryan@uphs.upenn.edu" class="auth_mail" title="E-mail the corresponding author ; Kathryn E. Demosd ; Kathryn_demos@brown.edu" class="auth_mail" title="E-mail the corresponding author ; Lisa Desiderioc ; lisa.desiderio@uphs.upenn.edu" class="auth_mail" title="E-mail the corresponding author ; Kirk I. Ericksone ; kiericks@pitt.edu" class="auth_mail" title="E-mail the corresponding author ; Mark A. Espelanda ; mespelan@wakehealth.edu" class="auth_mail" title="E-mail the corresponding author ; Ilya M. Nasrallahc ; ilya.nasrallah@uphs.upenn.edu" class="auth_mail" title="E-mail the corresponding author ; Thomas Waddenf ; wadden@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author ; Paul J. Laurientig ; plaurient@wakehealth.edu" class="auth_mail" title="E-mail the corresponding author ; for the Action for Health In Diabetes Brain Magnetic Resonance Imaging Look AHEAD Brain Ancillary Study Research Group.b
- 关键词：Resting-state fMRI ; Functional connectivity ; Type 2 diabetes mellitus ; Weight-loss intervention ; Brain networks
- 刊名：Psychoneuroendocrinology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：74
- 期：Complete
- 页码：231-239
- 全文大小：1284 K
文摘
- class="listitem" id="list_lis0005">
- class="label">•
The effect of a lifestyle intervention in adults with T2DM was examined using fMRI.
- class="label">•
Graph theory was used to compared between intervention and control groups (N = 312).
- class="label">•
Whole-brain local efficiency was reduced in the intervention group.
- class="label">•
Region-specific global efficiency was elevated in the intervention group.
- class="label">•
Intervention effects were age-dependent and more pronounced in older participants.