Measurements and detection of abdominal aortic aneurysm growth: Accuracy and reproducibility of a segmentation software

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• 作者：Claude Kauffmann ; An Tang ; ¨¦ric Therasse ; Marie-France Giroux ; Stephane Elkouri ; Philippe Melanson ; Bertr ; Melanson ; Vincent L. Oliva ; Gilles Soulez
• 关键词：AAA ; CTA ; Abdominal aortic aneurism ; 3D segmentation ; Follow-up ; D-max and volume growth
• 刊名：European Journal of Radiology
• 出版年：2012
• 出版时间：August, 2012
• 年：2012
• 卷：81
• 期：8
• 页码：1688-1694
• 全文大小：885 K

文摘

Purpose

To validate the reproducibility and accuracy of a software dedicated to measure abdominal aortic aneurysm (AAA) diameter, volume and growth over time.

Materials and methods

A software enabling AAA segmentation, diameter and volume measurement on computed tomography angiography (CTA) was tested. Validation was conducted in 28 patients with an AAA having 2 consecutive CTA examinations. The segmentation was performed twice by a senior radiologist and once by 3 medical students on all 56 CTAs. Intra and inter-observer reproducibility of D-max and volumes values were calculated by intraclass correlation coefficient (ICC). Systematic errors were evaluated by Bland-Altman analysis. Differences in D-max and volume growth were compared with paired Student's t-tests.

Results

Mean D-max and volume were 49.6 ¡À 6.2 mm and 117.2 ¡À 36.2 ml for baseline and 53.6 ¡À 7.9 mm and 139.6 ¡À 56.3 ml for follow-up studies. Volume growth (17.3 % ) was higher than D-max progression (8.0 % ) between baseline and follow-up examinations (p < .0001). For the senior radiologist, intra-observer ICC of D-max and volume measurements were respectively estimated at 0.997 (¡Ý0.991) and 1.000 (¡Ý0.999). Overall inter-observer ICC of D-max and volume measurements were respectively estimated at 0.995 (0.990-0.997) and 0.999 (>0.999). Bland-Altman analysis showed excellent inter-reader agreement with a repeatability coefficient <3 mm for D-max, <7 % for relative D-max growth, <6 ml for volume and <6 % for relative volume growth.

Conclusion

Software AAA volume measurements were more sensitive than AAA D-max to detect AAA growth while providing an equivalent and high reproducibility.