Central nervous system imaging findings of hemophagocytic syndrome

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• 作者：Tara L. Anderson ^{Anderson.Tara@mayo.edu" class="auth_mail" title="E-mail the corresponding author} ; Carrie M. Carr ; ^{Carr.Carrie@mayo.edu" class="auth_mail" title="E-mail the corresponding author} ; Timothy J. Kaufmann ^{Kaufmann.Timothy@mayo.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Hemophagocytic lymphohistiocytosis ; Inflammatory ; Central nervous system ; MRI
• 刊名：Clinical Imaging
• 出版年：2015
• 出版时间：November-December 2015
• 年：2015
• 卷：39
• 期：6
• 页码：1090-1094
• 全文大小：887 K

文摘

We present a rare case of intracranial involvement in hemophagocytic lymphohistiocytosis (HLH) in an adult patient. MRI features in HLH may mimic those of other neoplastic, infectious, or inflammatory disorders. Key imaging findings correlate to central nervous system inflammation and include diffuse leptomeningeal enhancement, white matter changes with variable enhancement, hemorrhage, and restricted diffusion. Recognition of the imaging characteristic in correlation with clinical presentation, laboratory values, and biopsy findings is essential for making a correct diagnosis.