Different etiologies and prognoses of optic neuritis in demyelinating diseases
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- 作者：Tetsuya Akaishia ; t-akaishi@med.tohoku.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Ichiro Nakashimaa ; nakashima@med.tohoku.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Takayuki Takeshitab ; takeshita.oph@me.com" class="auth_mail" title="E-mail the corresponding author ; Kimihiko Kanekoa ; k-kaneko@med.tohoku.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Shunji Mugikurac ; mugi844@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Douglas Kazutoshi Satoa ; douglas.sato@med.tohoku.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Toshiyuki Takahashia ; d ; t-toshiyuki@mta.biglobe.ne.jp" class="auth_mail" title="E-mail the corresponding author ; Toru Nakazawab ; ntoru@oph.med.tohoku.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Masashi Aokia ; aokim@med.tohoku.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Kazuo Fujiharaa ; e ; fujikazu@med.tohoku.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Multiple sclerosis ; Neuromyelitis optica spectrum disorder ; Anti-MOG autoantibody ; Optic neuritis ; Optic MRI ; Visual prognosis
- 刊名：Journal of Neuroimmunology
- 出版年：2016
- 出版时间：15 October 2016
- 年：2016
- 卷：299
- 期：Complete
- 页码：152-157
- 全文大小：652 K
文摘
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Optic neuritis (ON) in MS is younger-onset, shorter, and shows a better outcome.
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ON with serum anti-AQP4-Ab is female-dominant, older-onset, and shows a worse outcome.
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ON with serum anti-MOG-Ab is longer with swelling, but shows a better outcome.
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Idiopathic ON is much rarer compared to the three demyelinating diseases.
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Cerebral MRI and serum autoantibodies should be studied to make a correct diagnosis.