A total of 274 patients with acute spontaneous ICH were enrolled. ICAD and ECAD (moderate to severe stenosis or occlusion) were mainly assessed by intracranial magnetic resonance angiography and carotid duplex sonography, respectively.
Fifty-one patients (19 % ) had ICAD or ECAD; 32 had ICAD, and 21 had ECAD. On multivariable analyses, age (OR, 1.52; 95 % CI, 1.06-2.28 for every 10 years), monocyte count (OR, 1.37; 95 % CI, 1.02-1.87 for every 100/mm3), hemoglobin A1c (OR, 2.25; 95 % CI, 1.08-5.15 for every 1 % ), and low-density lipoprotein cholesterol levels (OR, 1.23; 95 % CI, 1.08-1.42 for every 10 mg/dL) were independently associated with ICAD. Age (OR, 2.20; 95 % CI, 1.20-4.38 for 10 years) and dyslipidemia (OR, 3.95; 95 % CI, 1.01-15.97) were independently associated with ECAD.
ICAD and ECAD were detected in approximately one-fifth of patients with spontaneous ICH. Age and dyslipidemia (or lipid profile) were associated with both ICAD and ECAD. Monocyte count and hemoglobin A1c were associated with ICAD.